COPENHAGEN—Older persons at risk for cog- nitive impairment improved in multiple areas of
cognition in a two-year study that focused on lifestyle
intervention, reported Miia Kivipelto, MD, PhD, at the
2014 Alzheimer’s Association International Conference.
“This is a proof-of-concept study giving the first evi-
dence from a large, long-term, multidomain, random-
ized controlled trial showing that we can reduce the risk
of cognitive impairment among older, at-risk individu-
als,” said Dr. Kivipelto, Professor of Clinical Geriatric
Epidemiology at the Karolinska Institutet Center for
Alzheimer Research in Stockholm and Professor at the
National Institute for Health and Welfare in Helsinki.
“The effect is not only limited to some areas of cogni-
tion, but we see it for several cognitive domains. [The
intervention is] feasible, people are able to follow it, and
there were no side effects.”
Dr. Kivipelto presented results from the Finnish
Geriatric Intervention Study to Prevent Cognitive Im-
pairment and Disability. The trial included 1,260 par-
ticipants (ages 60 to 77) who had modifiable risk
factors for cognitive impairment and Alzheimer’s
disease. Dr. Kivipelto’s group sought to reduce cog-
nitive impairment in an at-risk population through
Lifestyle Intervention
Improves Memory and Thinking
in Older Adults at Risk for Dementia
Serving the Neurology Community Since 1993
continued on page 4
Accountable Care Organizations
5 Aim to Provide Better Health Care
A Potential Smell Test
10 for Alzheimer’s Disease
A New Biomarker for
17 Alzheimer’s Disease?
Incidence of ALS Varies
20 by Race and Ethnicity
How Effective Are
23 Corticosteroids for Migraine?
34 for Creutzfeldt–Jakob Disease
Asthma May Increase Risk
Inside This Issue
©Shutt
erst
o
ck
