LONDON—Nine modifiable risk factors may ac- count for about a third of dementia cases, according
to an estimate by the Lancet International Commission
on Dementia Prevention, Intervention, and Care. The
estimate is part of a commission report that was presented at the 2017 Alzheimer’s Association International
Conference and published in Lancet.
The report reviews the evidence for pharmacologic,
psychologic, environmental, and social interventions for
patients with dementia. It includes algorithms for the
management of psychosis, agitation, and depression. And
it emphasizes the importance of assessing risks to patients
(eg, abuse and nutritional deficiencies), caring for family
caregivers, and future planning.
“There has been a great deal of focus on developing
medicines to prevent dementia,” said Lon S. Schneider,
MD, Professor of Psychiatry and Behavioral Sciences at
the Keck School of Medicine of University of Southern California in Los Angeles and one of the report’s
authors. “But we cannot lose sight of the … advances
we have already made in treating dementia, including
Nine Risk Factors
The authors reviewed the literature on dementia risk factors and estimated the potential percentage reduction in
new cases of dementia if a risk factor were eliminated
Can Targeting Risk
Factors Avert Dementia?
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